Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NTRK and RET fusion–directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake

8 Jul 2021

Abstract excerpt

BACKGROUNDMolecular characterization in pediatric papillary thyroid cancer (PTC), distinct from adult PTC, is important for developing molecularly targeted therapies for progressive radioiodine-refractory (131I-refractory) PTC.METHODSPTC samples from 106 pediatric patients (age range: 4.3-19.8 years; n = 84 girls, n = 22 boys) who were admitted to SNUH (January 1983-March 2020) were available for genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Thyroid Cancer Diagnosis and Treatment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34237031
DOI: 10.1172/jci144847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NTRK and RET fusion–directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptakePMID 34237031Read ↗

RET, NTRK, ALK, BRAF, and MET Fusions in a Large Cohort of Pediatric Papillary Thyroid Carcinomas.Semantic proximity Read ↗

Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma.Semantic proximity Read ↗

NTRK-fusions in pediatric thyroid tumors: Current state and future perspectives.Semantic proximity Read ↗

The clinical aspect of NTRK-fusions in pediatric papillary thyroid cancer.Semantic proximity Read ↗

Integrated DNA and RNA sequencing reveals targetable alterations in metastatic pediatric papillary thyroid carcinoma.Semantic proximity Read ↗

[Clinicopathological and molecular characteristics of pediatric and adolescent papillary thyroid carcinoma].Semantic proximity Read ↗

Distant Metastases From Childhood Differentiated Thyroid Carcinoma: Clinical Course and Mutational Landscape.Semantic proximity Read ↗

Sustained Response with Dose Reduced Selpercatinib in a Pediatric Patient with Metastatic NCOA4-RET Fusion Papillary Thyroid CarcinomaSemantic proximity Read ↗

Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.Semantic proximity Read ↗

Papillary and Follicular Thyroid Cancer in children and adolescents: Current approach and future directions.Semantic proximity Read ↗

Immunohistochemistry and Next-Generation Sequencing for NTRK Fusion detection in Differentiated Thyroid Cancer of Children, Adolescents and Young AdultsSemantic proximity Read ↗

High Prevalence of Gene Fusions and Copy Number Alterations in Pediatric Radiation Therapy-Induced Papillary and Follicular Thyroid Carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.