Article
RET, NTRK, ALK, BRAF, and MET Fusions in a Large Cohort of Pediatric Papillary Thyroid Carcinomas.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2020
Pekova Barbora, Sykorova Vlasta, Dvorakova Sarka, Vaclavikova Eliska, Moravcova Jitka, Katra Rami, Astl Jaromir, Vlcek Petr, Kodetova Daniela, Vcelak Josef, Bendlova Bela
Abstract excerpt
Background: Pediatric papillary thyroid carcinoma (PTC) is a rare malignancy, but with increasing incidence. Pediatric PTCs have distinct clinical and pathological features and even the molecular profile differs from adult PTCs. Somatic point mutations in pediatric PTCs have been previously described and studied, but complex information about fusion genes is lacking. The aim of this study was to identify...
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