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Article

Sustained Response with Dose Reduced Selpercatinib in a Pediatric Patient with Metastatic NCOA4-RET Fusion Papillary Thyroid Carcinoma

2023-01-23

Abstract excerpt

Understanding the molecular landscape of papillary thyroid carcinoma (PTC), the most common thyroid cancer in children, creates additional therapeutic approaches. RET gene rearrangements are observed in pediatric PTC and selective inhibition of RET is now possible with specific tyrosine kinase inhibitors designed to target diverse RET -activating mutations. We present a 13-year-old female with radioactive iodine...

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Literature Corpus work
735f3027-1e17-5b4b-bd7e-c4deca2690c1
DOI
10.22541/au.167446630.05113063/v1
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Sustained Response with Dose Reduced Selpercatinib in a Pediatric Patient with Metastatic NCOA4-RET Fusion Papillary Thyroid CarcinomaDOI 10.22541/au.167446630.05113063/v1
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