Article
Sustained Response with Dose Reduced Selpercatinib in a Pediatric Patient with Metastatic NCOA4-RET Fusion Papillary Thyroid Carcinoma
2023-01-23
Abstract excerpt
Understanding the molecular landscape of papillary thyroid carcinoma (PTC), the most common thyroid cancer in children, creates additional therapeutic approaches. RET gene rearrangements are observed in pediatric PTC and selective inhibition of RET is now possible with specific tyrosine kinase inhibitors designed to target diverse RET -activating mutations. We present a 13-year-old female with radioactive iodine...
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Identifiers and source
- Literature Corpus work
- 735f3027-1e17-5b4b-bd7e-c4deca2690c1
- DOI
- 10.22541/au.167446630.05113063/v1
