Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Prevalence of Gene Fusions and Copy Number Alterations in Pediatric Radiation Therapy-Induced Papillary and Follicular Thyroid Carcinomas.

Thyroid : official journal of the American Thyroid Association - 1 Apr 2022

Hess Jennifer R, Newbern Dorothee K, Beebe Kristen L, Walsh Alexandra M, Schafernak Kristian T

Abstract excerpt

Background: Childhood cancer survivors and bone marrow transplant recipients treated with radiation therapy (RT) are at increased risk for subsequent thyroid cancer. However, the genetic landscape of pediatric thyroid cancer, both primary and RT-induced, remains poorly defined, as pediatric papillary thyroid carcinoma (PTC) has been understudied compared with adults and data on pediatric follicular thyroid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Follicular
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DEAD-box RNA Helicases

Share to Gene Fusion

Share to Protein-Tyrosine Kinases

Share to Ribonuclease III

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 34915766
DOI: 10.1089/thy.2021.0217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High Prevalence of Gene Fusions and Copy Number Alterations in Pediatric Radiation Therapy-Induced Papillary and Follicular Thyroid Carcinomas.PMID 34915766Read ↗

Genetic alterations landscape in paediatric thyroid tumours and/or differentiated thyroid cancer: Systematic review.Semantic proximity Read ↗

Genomic landscape of sporadic pediatric differentiated thyroid cancers: a systematic review and meta-analysis.Semantic proximity Read ↗

Differentiated Thyroid Carcinoma in Pediatric Age: Genetic and Clinical ScenarioSemantic proximity Read ↗

RET, NTRK, ALK, BRAF, and MET Fusions in a Large Cohort of Pediatric Papillary Thyroid Carcinomas.Semantic proximity Read ↗

High Prevalence of DICER1 Mutations and Low Frequency of Gene Fusions in Pediatric Follicular-Patterned Tumors of the Thyroid.Semantic proximity Read ↗

Fusion Oncogenes Are the Main Genetic Events Found in Sporadic Papillary Thyroid Carcinomas from ChildrenSemantic proximity Read ↗

Evaluation of the genetic alterations landscape of differentiated thyroid cancer in children.Semantic proximity Read ↗

AGK‐BRAF is associated with distant metastasis and younger age in pediatric papillary thyroid carcinomaSemantic proximity Read ↗

Mutational analysis using next generation sequencing in pediatric thyroid cancer reveals BRAF and fusion oncogenes are common.Semantic proximity Read ↗

Thyroid Cancer In Children: A Multicenter International Study Highlighting Clinical Features And Surgical Outcomes Of Primary And Secondary TumorsSemantic proximity Read ↗

AGK-BRAF gene fusion is a recurrent event in sporadic pediatric thyroid carcinoma.Semantic proximity Read ↗

Clinicopathologic and Molecular Analysis of 15 Pediatric and Young Adult Patients with High-Grade Non-anaplastic Thyroid Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.