Article
Capture and On-chip analysis of Melanoma Cells Using Tunable Surface Shear forces.
Scientific reports - 27 Jan 2016
Tsao Simon Chang-Hao, Vaidyanathan Ramanathan, Dey Shuvashis, Carrascosa Laura G, Christophi Christopher, Cebon Jonathan, Shiddiky Muhammad J A, Behren Andreas, Trau Matt
Abstract excerpt
With new systemic therapies becoming available for metastatic melanoma such as BRAF and PD-1 inhibitors, there is an increasing demand for methods to assist with treatment selection and response monitoring. Quantification and characterisation of circulating melanoma cells (CMCs) has been regarded as an excellent non-invasive candidate but a sensitive and efficient tool to do these is lacking. Herein we...
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