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Article

Tempo-spatial regulation of the Wnt pathway by FAM13A modulates the stemness of alveolar epithelial progenitors

1 Jul 2021

Abstract excerpt

Background Family with Sequence Similarity 13, Member A (FAM13A) gene has been consistently associated with COPD by Genome-wide association studies (GWAS). Our previous study demonstrated that FAM13A was mainly expressed in the lung epithelial progenitors including Club cells and alveolar type II epithelial (ATII) cells. Fam13a −/− mice were resistant to cigarette smoke (CS)–induced emphysema through promoting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34224973
DOI: 10.1016/j.ebiom.2021.103463

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