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Article

S100a9 Protects Male Lupus-Prone NZBWF1 Mice From Disease Development.

Frontiers in immunology - 1 Jan 2021

Davison Laura M, Alberto Andres A, Dand Hardik A, Keller Emma J, Patt Madeline, Khan Ayesha, Dvorina Nina, White Alexandra, Sakurai Nodoka, Liegl Lauren N, Vogl Thomas, Jorgensen Trine N

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disorder disproportionally affecting women. A similar sex difference exists in the murine New Zealand Black/White hybrid model (NZBWF1) of SLE with all females, but only 30-40% of males, developing disease within the first year of life. Myeloid-derived suppressor cells (MDSCs) are prominent in NZBWF1 males and while depletion of these cells in males, but not...

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Identifiers

PMID: 34220829
DOI: 10.3389/fimmu.2021.681503
PMCID: PMC8248531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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