Article
Aurora kinase A is a target of Wnt/β-catenin involved in multiple myeloma disease progression
4 Aug 2009
Abstract excerpt
Multiple myeloma (MM) is a cancer of plasma cells with complex molecular characteristics that evolves from monoclonal gammopathy of undetermined significance, a highly prevalent premalignant condition. MM is the second most frequent hematologic cancer in the United States, and it remains incurable, thereby highlighting the need for new therapeutic approaches, particularly those targeting common molecular pathways...
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