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Article

Targeted base editing in the plastid genome of Arabidopsis thaliana.

Nature plants - 1 Jul 2021

Nakazato Issei, Okuno Miki, Yamamoto Hiroshi, Tamura Yoshiko, Itoh Takehiko, Shikanai Toshiharu, Takanashi Hideki, Tsutsumi Nobuhiro, Arimura Shin-Ichi

Abstract excerpt

Bacterial cytidine deaminase fused to the DNA binding domains of transcription activator-like effector nucleases was recently reported to transiently substitute a targeted C to a T in mitochondrial DNA of mammalian cultured cells1. We applied this system to targeted base editing in the Arabidopsis thaliana plastid genome. The targeted Cs were homoplasmically substituted to Ts in some plantlets of the T1...

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Identifiers

PMID: 34211131
DOI: 10.1038/s41477-021-00954-6
PMCID: PMC8289735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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