Article
Multiple gene substitution by Target-AID base-editing technology in tomato.
Scientific reports - 24 Nov 2020
Hunziker Johan, Nishida Keiji, Kondo Akihiko, Kishimoto Sanae, Ariizumi Tohru, Ezura Hiroshi
Abstract excerpt
The use of Target activation-induced cytidine deaminase (Target-AID) base-editing technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase (AID) resulted in the substitution of a cytidine with a thymine. In previous experiments focusing on a single target gene, this system has been reported to work in several plant species, including tomato (Solanum lycopersicum L.). In this...
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