Article
Association of Toll-like receptor 3 polymorphisms with chronic hepatitis B and hepatitis B-related acute-on-chronic liver failure.
Inflammation - 1 Apr 2013
Rong Yihui, Song Haihan, You Shaoli, Zhu Bing, Zang Hong, Zhao Yi, Li Yongli, Wan Zhihong, Liu Hongling, Zhang Aimin, Xiao Long, Xin Shaojie
Abstract excerpt
Hepatitis B virus (HBV) infection is one of the major causes of chronic liver inflammation. Toll-like receptor 3 (TLR3) plays a key role in innate immunity and is responsible for recognizing viral pathogens. It has been reported that the TLR3 C1234T polymorphism is associated with various diseases. The aim of this study was to investigate whether TLR3 polymorphisms were correlated with susceptibility to chronic...
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