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Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood

11 Sept 2015

Abstract excerpt

Childhood obesity is a major public health issue. Here we investigated whether differential DNA methylation was associated with childhood obesity. We studied DNA methylation profiles in whole blood from 78 obese children (mean BMI Z-score: 2.6) and 71 age- and sex-matched controls (mean BMI Z-score: 0.1). DNA samples from obese and control groups were pooled and analyzed using the Infinium HumanMethylation450...

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PMID: 26646899
DOI: 10.1080/15592294.2015.1080411

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