Article
An Epigenome-Wide Association Study of Obesity-Related Traits.
American journal of epidemiology - 1 Aug 2018
Dhana Klodian, Braun Kim V E, Nano Jana, Voortman Trudy, Demerath Ellen W, Guan Weihua, Fornage Myriam, van Meurs Joyce B J, Uitterlinden Andre G, Hofman Albert, Franco Oscar H, Dehghan Abbas
Abstract excerpt
We conducted an epigenome-wide association study on obesity-related traits. We used data from 2 prospective, population-based cohort studies: the Rotterdam Study (RS) (2006-2013) and the Atherosclerosis Risk in Communities (ARIC) Study (1990-1992). We used the RS (n = 1,450) as the discovery panel and the ARIC Study (n = 2,097) as the replication panel. Linear mixed-effect models were used to assess the...
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