Article
GHRL, LEP, LEPR genes polymorphism and their association with the metabolic syndrome in the Ukrainian population.
Endocrine regulations - 1 Jan 2023
Prodan Andrii, Dzubanovsky Ihor, Kamyshnyi Oleksandr, Melnyk Natalia, Pidruchna Svitlana, Voloshyn Stanislava
Abstract excerpt
Objective. Many conflicting results have been obtained in the study of leptin (LEP) and leptin receptor (LEPR) gene variants that are associated with the obesity and diabetes possibly due to differences in the study populations. The aim of this study was to evaluate changes in the metabolic hormones (leptin, ghrelin, adiponectin, resistin) levels in the blood of obese patients in relation to the GHRL (rs696217),...
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