Article
Polymorphisms in Genes Involved in the Leptin-Melanocortin Pathway are Associated with Obesity-Related Cardiometabolic Alterations in a Southern Chilean Population.
Molecular diagnosis & therapy - 1 Feb 2018
Manriquez Victor, Aviles Jorge, Salazar Luis, Saavedra Nicolas, Seron Pamela, Lanas Fernando, Fajardo Cristina Moreno, Hirata Mario Hiroyuki, Hirata Rosario Dominguez Crespo, Cerda Alvaro
Abstract excerpt
BACKGROUND: Polymorphisms in genes encoding proteins of the leptin-melanocortin pathway have been associated with obesity. The involvement of these polymorphisms with changes in body mass index (BMI) and anthropometric measures could also imply a contribution to the risk of metabolic syndrome (MetS) and metabolic alterations. We evaluated the relationship of leptin-melanocortin system polymorphisms with obesity,...
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