Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico Approach

4 Jun 2021

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) are reported to be associated with many diseases, including autoimmune diseases. In rheumatoid arthritis (RA), about 152 SNPs are reported to account for ~15% of its heritability. These SNPs may result in the alteration of gene expression and may also affect the stability of mRNA, resulting in diseased protein. Therefore, in order to predict the underlying mechanism of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Monoclonal and Polyclonal Antibodies Research
Share to Protein Tyrosine Phosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34199962
DOI: 10.3390/biology10060501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of Rheumatoid Arthritis Risk-Associated SNPs and Identification of Novel Therapeutic Sites Using an In-Silico ApproachPMID 34199962Read ↗

Genetic markers as therapeutic target in rheumatoid arthritis: A game changer in clinical therapy?Semantic proximity Read ↗

Update on the genetic architecture of rheumatoid arthritis.Semantic proximity Read ↗

RADB: a database of rheumatoid arthritis-related polymorphisms.Semantic proximity Read ↗

Genetics of rheumatoid arthritis contributes to biology and drug discovery.Semantic proximity Read ↗

Integrative analyses for functional mechanisms underlying associations for rheumatoid arthritis.Semantic proximity Read ↗

The genetic puzzle of rheumatoid arthritis: Causes, progression, and treatmentSemantic proximity Read ↗

Identifying therapeutic targets for rheumatoid arthritis by genomics-driven integrative approachesSemantic proximity Read ↗

Prediction of New Risk Genes and Potential Drugs for Rheumatoid Arthritis from Multiomics Data.Semantic proximity Read ↗

The Functional Impact of Alternative Splicing and Single Nucleotide Polymorphisms in Rheumatoid Arthritis.Semantic proximity Read ↗

Synovial transcriptome-wide association study implicates novel genes underlying rheumatoid arthritis risk.Semantic proximity Read ↗

Susceptibility genes for rheumatoid arthritis - a rapidly expanding harvest.Semantic proximity Read ↗

From the era of genome analysis to the era of genomic drug discovery: a pioneering example of rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.