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Article

Next generation sequencing in therapy-related myeloid neoplasms compared to de novo myeloid neoplasms.

Acta clinica Belgica - 1 Jun 2022

Claerhout Helena, Vranckx Hilde, Lierman Els, Michaux Lucienne, Boeckx Nancy

Abstract excerpt

INTRODUCTION: Therapy-related myeloid neoplasms (t-MN) are frequently categorized according to previous therapy or pattern of cytogenetic abnormalities. Our objective was to evaluate and compare the mutational profile of de novo and t-MN by next generation sequencing. METHODS: Sixty-four samples from patients with t-MN, previously treated for a solid tumor (mainly breast), or de novo AML, MDS, MDS/MPN were...

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Identifiers

PMID: 34197279
DOI: 10.1080/17843286.2021.1943232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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