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Article

Routine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms.

Oncotarget - 24 May 2016

Bartels Stephan, Schipper Elisa, Hasemeier Britta, Kreipe Hans, Lehmann Ulrich

Abstract excerpt

Microscopic examination of myelodysplastic syndromes (MDS) and myelodysplastic-myeloproliferative neoplasms (MDS/MPN) may be challenging because morphological features can overlap with those of reactive states. Demonstration of clonal hematopoiesis provides a diagnostic clue and has become possible by comprehensive mutation profiling of a number of frequently mutated genes, some of them with large coding...

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Source

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Identifiers

PMID: 27029036
DOI: 10.18632/oncotarget.8310
PMCID: PMC5058665

Genes

ASXL1
SRSF2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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