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Article

The role of clonal progression leading to the development of therapy-related myeloid neoplasms.

Annals of hematology - 1 Sept 2024

Guarnera Luca, Pascale Maria Rosaria, Hajrullaj Hajro, Cristiano Antonio, Mallegni Flavia, Onorato Angelo, Voso Maria Teresa, Fabiani Emiliano

Abstract excerpt

Therapy-related myeloid neoplasms (t-MN) are characterized by aggressive features and a dismal prognosis. Recent evidence suggests a higher incidence of t-MN in individuals harboring clonal hematopoiesis of indeterminate potential (CHIP). In order to gain insight into CHIP-driven malignant progression, we gathered data from ten published reports with available detailed patient characteristics at the time of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39031199
DOI: 10.1007/s00277-024-05803-y
PMCID: PMC11358309

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