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Article

Association of FOXP3 Gene Variants with Risk Of Hashimoto’s Thyroiditis and Correlation with Anti-TPO Antibody Levels

1 Jan 2019

Abstract excerpt

CONTEXT: Regulatory T cells (Tregs) have critical roles in preventing autoimmune diseases such as Hashimoto's thyroiditis (HT). Forkhead box P3 (Foxp3), the master transcription factor of Tregs, plays a pivotal role in Treg function. OBJECTIVE: Herein, we investigated the association of two single nucleotide polymorphisms (SNPs) of the Foxp3 gene with HT development. METHODS AND STUDY DESIGN: A total of 129 HT...

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Identifiers

PMID: 32377237
DOI: 10.4183/aeb.2019.423

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