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Article

Genetic polymorphisms of Foxp3 in patients with rheumatoid arthritis.

The Journal of rheumatology - 1 Feb 2015

Paradowska-Gorycka Agnieszka, Jurkowska Monika, Felis-Giemza Anna, Romanowska-Próchnicka Katarzyna, Manczak Malgorzata, Maslinski Slawomir, Olesinska Marzena

Abstract excerpt

OBJECTIVE: The aim of the study was to identify 2 polymorphic variants in the promoter region of the Foxp3 gene and their possible association with susceptibility to and severity of rheumatoid arthritis (RA). The association between genetic factors and pathogenesis suggests that T cells take part in the induction of RA. The CD4+CD25highFoxp3+ subset of regulatory T cells plays an essential role in preventing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25448791
DOI: 10.3899/jrheum.131381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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