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Article

Genetic polymorphism in FOXP3 gene: imbalance in regulatory T-cell role and development of human diseases.

Journal of genetics - 1 Apr 2013

Oda Julie Massayo Maeda, Hirata Bruna Karina Banin, Guembarovski Roberta Losi, Watanabe Maria Angelica Ehara

Abstract excerpt

The FOXP3 gene encodes a transcription factor thought to be important for the development and function of regulatory T cells (Treg cells). These cells are involved in the regulation of T cell activation and therefore are essential for normal immune homeostasis. Signals from microenvironment have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23640423
DOI: 10.1007/s12041-013-0213-7

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23640423-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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