Article
FOXP3 rs3761548 polymorphism is associated with knee osteoarthritis in a Turkish population.
International journal of rheumatic diseases - 1 Oct 2018
Cekin Nilgun, Pinarbasi Ergun, Bildirici Aslıhan Esra, Donmez Gonca, Oztemur Zekeriya, Bulut Okay, Arslan Serdal
Abstract excerpt
AIM: Functional polymorphisms located in FOXP3 intron 1 was recently found to be associated with rheumatoid arthritis (RA). Although RA is an autoimmune disease, there is supporting evidence that activated maladaptive responses including pro-inflammatory pathways play roles in osteoarthritis (OA), similar to RA. The aim of this study was to explore the relationship between rs2232365 (-924A/G) and rs3761548...
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