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Article

IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome Stability

28 Jun 2021

Abstract excerpt

Abstract Controlling cell proliferation is critical for organism development, tissue homeostasis, disease, and regeneration. IQGAP3 has been shown to be required for proper cell proliferation and migration, and is associated to a number of cancers. Moreover, its expression is inversely correlated with the overall survival rate in the majority of cancers. Here, we show that IQGAP3 expression is elevated in...

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PMID: 34183451
DOI: 10.1158/1541-7786.mcr-20-0639

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