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Article

Genetic polymorphisms of regulatory T cell-related genes modulate systemic inflammation induced by viral hepatitis.

The Kaohsiung journal of medical sciences - 1 Nov 2021

Kao Hsueh-Hsin, Yu Rwei-Ling, Chuang Wan-Long, Huang Jee-Fu, Dai Chia-Yen, Tan Chun-Hsiang

Abstract excerpt

Viral hepatitis is a devastating disease with the risk for cirrhosis and carcinogenicity. Regulatory T cells (Tregs) play important roles in the disease course of viral hepatitis via maintaining the balance between overt-immune responses and viral replications. We hypothesized that genetic polymorphisms of Treg-related genes, such as interleukin-2, transforming growth factor-β 1 (TGF-β1), forkhead box P3 (FOXP3),...

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Identifiers

PMID: 34166564
DOI: 10.1002/kjm2.12414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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