Article
Association between IL28B rs12979860 single nucleotide polymorphism and the frequency of colonic Treg in chronically HCV-infected patients.
Archives of virology - 1 Nov 2016
Mehta Minesh, Hetta Helal F, Abdel-Hameed Enass A, Rouster Susan D, Hossain MdMonir, Mekky Mohamed A, Khalil Nasr K, Mohamed Wegdan A, El-Feky Mohamed A, Ahmed Shabaan H, Daef Enas A, El-Mokhtar Mohamed A, Abdelwahab Sayed F, Medhat Ahmed, Sherman Kenneth E, Shata Mohamed Tarek M
Abstract excerpt
The IL28B gene is associated with spontaneous or treatment-induced HCV viral clearance. However, the mechanism by which the IL28B single nucleotide polymorphism (SNP) affects the extra-hepatic HCV immune responses and its relationship to HCV pathogenesis have not been thoroughly investigated. To examine the mechanism by which IL28B affects HCV clearance. Forty Egyptian patients with chronic HCV infection...
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