Association of Foxp3 rs3761548 polymorphism with cytokines concentration in gastric adenocarcinoma patients.

doi:10.1016/j.cyto.2020.155351

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Association of Foxp3 rs3761548 polymorphism with cytokines concentration in gastric adenocarcinoma patients.

Cytokine - 1 Feb 2021

Ezzeddini Rana, Somi Mohammad Hossein, Taghikhani Mohammad, Moaddab Seyyed-Yaghoub, Masnadi Shirazi Kourosh, Shirmohammadi Masoud, Eftekharsadat Amir Taher, Sadighi Moghaddam Bizhan, Salek Farrokhi Amir

Abstract excerpt

T regulatory cells (Tregs) and related-cytokines are effectively engaged in the process of tumor immune escape and functionally inhibit immune response against the tumor. This study aimed to investigate the association of Foxp3 gene single nucleotide polymorphism (SNP) (rs3761548) with serum IL-35, IL-10, and TGF-β levels in gastric adenocarcinoma (GA) patients. The blood samples were obtained from 150 GA...

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PMID: 33127257
DOI: 10.1016/j.cyto.2020.155351

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