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Article

FOXP3 variants are independently associated with transforming growth factor Β1 plasma levels in female patients with inflammatory bowel disease.

Clinics (Sao Paulo, Brazil) - 1 Jan 2022

Inoue Cláudia Junko, Flauzino Tamires, Gonçalves Beatriz Piantoni, Paula Jaqueline Costa Castardo de, Galvão Talita Cristina, Miyazaki Paula Kikuchi, Alcantara Camila Cataldi de, Westmore Lucilene Rosa E Silva, Lozovoy Marcell Alysson Batisti, Reiche Edna Maria Vissoci, Simão Andréa Name Colado

Abstract excerpt

OBJECTIVE: The aim of this study was to evaluate the association of -924 G>A (rs2232365) and -3279 C>A (rs3761548) FOXP3 variants with IBD susceptibility, clinical and endoscopic activity, and IL-10 and TGF-β1 plasma levels. METHOD: The study included 110 IBD female patients, 60 with Ulcerative Colitis (UC) and 50 with Crohn's Disease (CD), and 154 female controls. FOXP3 variants were determined with Polymerase...

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Share to Colitis, Ulcerative
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Share to Forkhead Transcription Factors
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Identifiers

PMID: 35905575
DOI: 10.1016/j.clinsp.2022.100084
PMCID: PMC9335380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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