Article
Effect of immunogenetics polymorphism and expression on direct-acting antiviral drug response in chronic hepatitis C.
Clinical and experimental medicine - 8 Aug 2024
Abdelaziz Aya Ismail, Abdelsameea Eman, Abdel-Samiee Mohamed, Ghanem Samar E, Wahdan Sara A, Elsherbiny Doaa A, Zakaria Zeinab, Azab Samar S
Abstract excerpt
The prevalence of HCV infection in Egypt has decreased following the introduction of direct-acting antiviral therapy. However, treatment response is influenced by various factors, particularly host immunogenetics such as IL-28B and FOXP3 polymorphisms. The current study examined the impact of SNPs in the FOXP3 gene promoter region on HCV-infected Egyptian patients, along with SNPs in the IL28B gene.This study...
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