Cerebral Cavernous Malformation: From Mechanism to Therapy.

doi:10.1161/CIRCRESAHA.121.318174

Article

Cerebral Cavernous Malformation: From Mechanism to Therapy.

Circulation research - 25 Jun 2021

Snellings Daniel A, Hong Courtney C, Ren Aileen A, Lopez-Ramirez Miguel A, Girard Romuald, Srinath Abhinav, Marchuk Douglas A, Ginsberg Mark H, Awad Issam A, Kahn Mark L

Abstract excerpt

Cerebral cavernous malformations are acquired vascular anomalies that constitute a common cause of central nervous system hemorrhage and stroke. The past 2 decades have seen a remarkable increase in our understanding of the pathogenesis of this vascular disease. This new knowledge spans genetic c...

Topics

Animals
Cerebral Veins
Genetic Predisposition to Disease
Hemangioma, Cavernous, Central Nervous System
Humans
Mutation
Phenotype
Signal Transduction

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