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Article

Cerebral cavernous malformations as a disease of vascular permeability: from bench to bedside with caution.

Neurosurgical focus - 1 Sept 2010

Yadla Sanjay, Jabbour Pascal M, Shenkar Robert, Shi Changbin, Campbell Peter G, Awad Issam A

Abstract excerpt

Tremendous insight into the molecular and genetic pathogenesis of cerebral cavernous malformations (CCMs) has been gained over the past 2 decades. This includes the identification of 3 distinct genes involved in familial CCMs. Still, a number of unanswered questions regarding the process from gene mutation to vascular malformation remain. It is becoming more evident that the disruption of interendothelial...

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Identifiers

PMID: 20809762
DOI: 10.3171/2010.5.FOCUS10121
PMCID: PMC6599630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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