Article
Biology of vascular malformations of the brain.
Stroke - 1 Dec 2009
Leblanc Gabrielle G, Golanov Eugene, Awad Issam A, Young William L
Abstract excerpt
BACKGROUND AND PURPOSE: This review discusses recent research on the genetic, molecular, cellular, and developmental mechanisms underlying the etiology of vascular malformations of the brain (VMBs), including cerebral cavernous malformation, sporadic brain arteriovenous malformation, and the arteriovenous malformations of hereditary hemorrhagic telangiectasia. Summary of Review- The identification of gene...
Topics
- Animals
- Cerebral Arteries
- Disease Models, Animal
- Gene Expression Regulation, Developmental
- Genetic Predisposition to Disease
- Hemangioma, Cavernous, Central Nervous System
- Humans
- Intracranial Arteriovenous Malformations
- Mutation
- Neovascularization, Pathologic
- Telangiectasia, Hereditary Hemorrhagic
