Cerebral cavernous malformations - An overview on genetics, clinical aspects and therapeutic strategies.

Abstract excerpt

Cerebral cavernous malformations (CCMs) are abnormally packed blood vessels lined with endothelial cells, that do not exhibit intervening tight junctions, lack muscular and elastic layers and are usually surrounded by hemosiderin and gliosis. CCMs may be sporadic or familial autosomal dominant (F...

Topics

• Humans
• Hemangioma, Cavernous, Central Nervous System
• Mutation