Article
Chromatin Regulation at Parental Gene Promoters by Pseudogene Sense lncRNAs.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Schoeftner Stefan, Scarola Michele, Benetti Roberta
Abstract excerpt
There is accumulating evidence that pseudogenes can produce functionally relevant lncRNAs in a tightly controlled manner. This class of transcripts has been demonstrated to play an important role in development and disease, by controlling parental gene expression. Classically, pseudogene derived lncRNAs compete with parental transcripts for miRNAs or factors that control parental mRNA metabolisms. Recently,...
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