Article
Combining single-cell profiling and functional analysis explores the role of pseudogenes in human early embryonic development.
Journal of genetics and genomics = Yi chuan xue bao - 1 Nov 2024
Sun Mengyao, Chang Le, He Liu, Wang Li, Jiang Zhengyang, Si Yanmin, Yu Jia, Ma Yanni
Abstract excerpt
More and more studies have demonstrated that pseudogenes possess coding ability, and the functions of their transcripts in the development of diseases have been partially revealed. However, the role of pseudogenes in maintenance of normal physiological states and life activities has long been neglected. Here, we identify pseudogenes that are dynamically expressed during human early embryogenesis, showing...
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