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Article

Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons.

Cell reports - 22 Jun 2021

Tsyporin Jeremiah, Tastad David, Ma Xiaokuang, Nehme Antoine, Finn Thomas, Huebner Liora, Liu Guoping, Gallardo Daisy, Makhamreh Amr, Roberts Jacqueline M, Katzman Solomon, Sestan Nenad, McConnell Susan K, Yang Zhengang, Qiu Shenfeng, Chen Bin

Abstract excerpt

Projection neuron subtype identities in the cerebral cortex are established by expressing pan-cortical and subtype-specific effector genes that execute terminal differentiation programs bestowing neurons with a glutamatergic neuron phenotype and subtype-specific morphology, physiology, and axonal projections. Whether pan-cortical glutamatergic and subtype-specific characteristics are regulated by the same genes...

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Identifiers

PMID: 34161768
DOI: 10.1016/j.celrep.2021.109269
PMCID: PMC8327856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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