Article

A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification

2023-09-13

Abstract excerpt

Human brain development requires the generation of hundreds of diverse cell types, a process targeted by recent single-cell transcriptomic profiling efforts. Through a meta-analysis of seven of these published datasets, we have generated 225 meta-modules – gene co-expression networks that can describe mechanisms underlying cortical development. Several meta-modules have potential roles in both establishing and ref...

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Literature Corpus work: 5afa6c38-b191-5004-aca5-bd1d1312a087
DOI: 10.1101/2023.09.12.557406

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