Article
The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex.
Proceedings of the National Academy of Sciences of the United States of America - 12 Aug 2008
Chen Bin, Wang Song S, Hattox Alexis M, Rayburn Helen, Nelson Sacha B, McConnell Susan K
Abstract excerpt
Pyramidal neurons in the deep layers of the cerebral cortex can be classified into two major classes: callosal projection neurons and long-range subcortical neurons. We and others have shown that a gene expressed specifically by subcortical projection neurons, Fezf2, is required for the formation of axonal projections to the spinal cord, tectum, and pons. Here, we report that Fezf2 regulates a decision between...
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