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Obesity, oxidative DNA damage and vitamin D as predictors of genomic instability in children and adolescents

22 Jun 2021

Abstract excerpt

BACKGROUND/OBJECTIVES: Epidemiological evidence indicates obesity in childhood and adolescence to be an independent risk factor for cancer and premature mortality in adulthood. Pathological implications from excess adiposity may begin early in life. Obesity is concurrent with a state of chronic inflammation, a well-known aetiological factor for DNA damage. In addition, obesity has been associated with...

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PMID: 34158611
DOI: 10.1038/s41366-021-00879-2

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