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Obesity-related genomic instability and altered xenobiotic metabolism: possible consequences for cancer risk and chemotherapy

1 Jan 2022

Abstract excerpt

The increase in the prevalence of obesity has led to an elevated risk for several associated diseases including cancer. Several studies have investigated the DNA damage in human blood samples and showed a clear trend towards increased DNA damage in obesity. Reduced genomic stability is thus one of the consequences of obesity, which may contribute to the related cancer risk. Whether this is influenced by...

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PMID: 35899852
DOI: 10.1017/erm.2022.22

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