Article
Robustification of GWAS to explore effective SNPs addressing the challenges of hidden population stratification and polygenic effects.
Scientific reports - 22 Jun 2021
Akond Zobaer, Ahsan Md Asif, Alam Munirul, Mollah Md Nurul Haque
Abstract excerpt
Genome-wide association studies (GWAS) play a vital role in identifying important genes those is associated with the phenotypic variations of living organisms. There are several statistical methods for GWAS including the linear mixed model (LMM) which is popular for addressing the challenges of hidden population stratification and polygenic effects. However, most of these methods including LMM are sensitive to...
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