Article
A SUPER powerful method for genome wide association study.
PloS one - 1 Jan 2014
Wang Qishan, Tian Feng, Pan Yuchun, Buckler Edward S, Zhang Zhiwu
Abstract excerpt
Genome-Wide Association Studies shed light on the identification of genes underlying human diseases and agriculturally important traits. This potential has been shadowed by false positive findings. The Mixed Linear Model (MLM) method is flexible enough to simultaneously incorporate population structure and cryptic relationships to reduce false positives. However, its intensive computational burden is prohibitive...
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