Article
On the use of GBLUP and its extension for GWAS with additive and epistatic effects.
G3 (Bethesda, Md.) - 14 Jul 2021
Zhang Jie, Liu Fang, Reif Jochen C, Jiang Yong
Abstract excerpt
Genomic best linear unbiased prediction (GBLUP) is the most widely used model for genome-wide predictions. Interestingly, it is also possible to perform genome-wide association studies (GWAS) based on GBLUP. Although the estimated marker effects in GBLUP are shrunken and the conventional test based on such effects has low power, it was observed that a modified test statistic can be produced and the result of test...
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