Article
An efficient unified model for genome-wide association studies and genomic selection.
Genetics, selection, evolution : GSE - 24 Aug 2017
Li Hengde, Su Guosheng, Jiang Li, Bao Zhenmin
Abstract excerpt
BACKGROUND: A quantitative trait is controlled both by major variants with large genetic effects and by minor variants with small effects. Genome-wide association studies (GWAS) are an efficient approach to identify quantitative trait loci (QTL), and genomic selection (GS) with high-density single nucleotide polymorphisms (SNPs) can achieve higher accuracy of estimated breeding values than conventional best...
Topics
- Animals
- Bayes Theorem
- Breeding
- Genome-Wide Association Study
- Genomics
- Models, Genetic
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Selection, Genetic