Article
Altered germline cyst formation and oogenesis in Tex14 mutant mice.
Biology open - 15 Jun 2021
Ikami Kanako, Nuzhat Nafisa, Abbott Haley, Pandoy Ronald, Haky Lauren, Spradling Allan C, Tanner Heather, Lei Lei
Abstract excerpt
During oocyte differentiation in mouse fetal ovaries, sister germ cells are connected by intercellular bridges, forming germline cysts. Within the cyst, primary oocytes form via gaining cytoplasm and organelles from sister germ cells through germ cell connectivity. To uncover the role of intercellular bridges in oocyte differentiation, we analyzed mutant female mice lacking testis-expressed 14 (TEX14), a protein...
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