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Branched germline cysts and female-specific cyst fragmentation facilitate oocyte determination in mice

8 May 2023

Abstract excerpt

During mouse gametogenesis, germ cells derived from the same progenitor are connected via intercellular bridges forming germline cysts, within which asymmetrical or symmetrical cell fate occurs in female and male germ cells, respectively. Here, we have identified branched cyst structures in mice, and investigated their formation and function in oocyte determination. In fetal female cysts, 16.8% of the germ cells...

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PMID: 37155904
DOI: 10.1073/pnas.2219683120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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