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Article

Mouse oocytes develop in cysts with the help of nurse cells

2021-11-04

Abstract excerpt

<h4>Summary</h4> Mammalian oocytes develop initially in cysts containing many more germ cells than the primordial oocytes they generate. We identified abundant nurse cells with reduced unique molecular identifiers (UMI)/cell from ovaries aged E14.5 to P1. Low UMI nurse cells are found in cysts and express the same major meiotic genes as pro-oocytes of the same stage, suggesting they are oocyte sisters that are si...

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Literature Corpus work
63d48d0b-893f-5800-a75f-a4318d1bd0f2
DOI
10.1101/2021.11.04.467284
Open publication

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Mouse oocytes develop in cysts with the help of nurse cellsDOI 10.1101/2021.11.04.467284
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