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Article

Intact fetal ovarian cord formation promotes mouse oocyte survival and development

8 Jan 2010

Abstract excerpt

BACKGROUND: Female reproductive potential, or the ability to propagate life, is limited in mammals with the majority of oocytes lost before birth. In mice, surviving perinatal oocytes are enclosed in ovarian follicles for subsequent oocyte development and function in the adult. Before birth, fetal germ cells of both sexes develop in clusters, or germline cysts, in the undifferentiated gonad. Upon sex...

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PMID: 20064216
DOI: 10.1186/1471-213x-10-2

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