Article
Mouse germ cell clusters form by aggregation as well as clonal divisions.
Mechanisms of development - 1 Jan 2000
Mork Lindsey, Tang Hao, Batchvarov Iordan, Capel Blanche
Abstract excerpt
After their arrival in the fetal gonad, mammalian germ cells express E-cadherin and are found in large clusters, similar to germ cell cysts in Drosophila. In Drosophila, germ cells in cysts are connected by ring canals. Several molecular components of intercellular bridges in mammalian cells have been identified, including TEX14, a protein required for the stabilization of intercellular bridges, and several...
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