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Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells

25 Feb 2016

Abstract excerpt

Oocytes differentiate in diverse species by receiving organelles and cytoplasm from sister germ cells while joined in germline cysts or syncytia. Mouse primordial germ cells form germline cysts, but the role of cysts in oogenesis is unknown. We find that mouse germ cells receive organelles from neighboring cyst cells and build a Balbiani body to become oocytes, whereas nurselike germ cells die. Organelle...

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Identifiers

PMID: 26917595
DOI: 10.1126/science.aad2156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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